Batch Precipitations Seminar
Precision Crystallization in Controlled Batch Reactors
Introduction to Factors affecting Crystallization
Review of prior Nucleation Models
The Balanced Nucleation and Growth (BNG) Model
The Nucleation Phase
- Modeling Factors for Crystal Size and Size Distribution
- Critical Cluster Size
- Nucleation Efficiency
- Maximum Crystal Growth Rate
- Reactant Addition Rate
The Analytical Model and Experiments
Nucleation under Diffusion controlled Growth Conditions
- Surface Energy, Supersaturation, Diffusion Rate
- Temperature
- Solubility
- Addition Rate
- Ostwald Ripening Agents – Macro-Sizing
- Renucleation
Nucleation under Kinetically controlled Growth Conditions
- Time-Dependence of Nucleation
- Kinetic Integration Constant
- Growth Restrainers – Nano-Sizing
Questions and Answers
