Controlled Continuous Precipitations Seminar
Precision Crystallization in the Continuous Stirred Tank Reactor (CSTR, Mixed Suspension and Mixed Product Removal, MSMPR), Plug-Flow Reactor, and Seeded CSTR Reactor
Review of the prior Randolph – Larsen Model
The Balanced Nucleation and Growth (BNB) Model
Crystal Size as a Function of:
- Suspension Density
- Reaction Addition Rate
- Residence Time
- Solubility
- Temperature
Derived Reaction Information:
- Supersaturation and Supersaturation Ratio
- Maximum Growth Rate of Crystals
- Nascent Nuclei Size
- Critical Crystal Size
- Nucleation Rate
- Growth/Nucleation Ratio
Crystal Growth in Seeded CSTR Crystallizations:
Factors determining Crystal Growth, Size, and Size Distribution:
- Seed Addition Rate
- Seed Size
- Seed Morphology
- Reactant Addition Rate
- Reactor Residence Time
